Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Nrp1  neuropilin 1   (Synonyms: Neuropilin-1, NP-1, Npn1, NPN-1)
Results	Reference
1	J:65909 Abbott BD, Buckalew AR, Placental defects in ARNT-knockout conceptus correlate with localized decreases in VEGF-R2, ang-1, and tie-2. Dev Dyn. 2000 Dec;219(4):526-38
1	J:161794 Catela C, Kratsios P, Hede M, Lang F, Rosenthal N, Serum and glucocorticoid-inducible kinase 1 (SGK1) is necessary for vascular remodeling during angiogenesis. Dev Dyn. 2010 Aug;239(8):2149-60
1	J:174608 Chong DC, Koo Y, Xu K, Fu S, Cleaver O, Stepwise arteriovenous fate acquisition during mammalian vasculogenesis. Dev Dyn. 2011 Sep;240(9):2153-65
1	J:174085 Cunningham K, Uchida Y, O'Donnell E, Claudio E, Li W, Soneji K, Wang H, Mukouyama YS, Siebenlist U, Conditional deletion of Ccm2 causes hemorrhage in the adult brain: a mouse model of human cerebral cavernous malformations. Hum Mol Genet. 2011 Aug 15;20(16):3198-206
1	J:330268 De Zoysa P, Toubat O, Harvey DC, Yi C, Liu J, Cavallero S, Hong YK, Sucov HM, Kumar SR, Delta-like ligand-4 regulates Notch-mediated maturation of second heart field progenitor-derived pharyngeal arterial endothelial cells. J Cell Mol Med. 2022 Oct;26(20):5181-5194
1	J:198676 Degenhardt K, Singh MK, Aghajanian H, Massera D, Wang Q, Li J, Li L, Choi C, Yzaguirre AD, Francey LJ, Gallant E, Krantz ID, Gruber PJ, Epstein JA, Semaphorin 3d signaling defects are associated with anomalous pulmonary venous connections. Nat Med. 2013 Jun;19(6):760-5
1*	J:176047 Fantin A, Schwarz Q, Davidson K, Normando EM, Denti L, Ruhrberg C, The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins. Development. 2011 Oct;138(19):4185-91
1	J:89444 Fischer A, Schumacher N, Maier M, Sendtner M, Gessler M, The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev. 2004 Apr 15;18(8):901-11
1*	J:137168 Gordon EJ, Gale NW, Harvey NL, Expression of the hyaluronan receptor LYVE-1 is not restricted to the lymphatic vasculature; LYVE-1 is also expressed on embryonic blood vessels. Dev Dyn. 2008 Jul;237(7):1901-9
1	J:224939 Hare LM, Schwarz Q, Wiszniak S, Gurung R, Montgomery KG, Mitchell CA, Phillips WA, Heterozygous expression of the oncogenic Pik3ca(H1047R) mutation during murine development results in fatal embryonic and extraembryonic defects. Dev Biol. 2015 Aug 1;404(1):14-26
1	J:187616 Maden CH, Gomes J, Schwarz Q, Davidson K, Tinker A, Ruhrberg C, NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system. Dev Biol. 2012 Sep 15;369(2):277-85
1	J:152700 Mancini ML, Terzic A, Conley BA, Oxburgh LH, Nicola T, Vary CP, Endoglin plays distinct roles in vascular smooth muscle cell recruitment and regulation of arteriovenous identity during angiogenesis. Dev Dyn. 2009 Aug 24;238(10):2479-2493
1	J:270163 Neal A, Nornes S, Payne S, Wallace MD, Fritzsche M, Louphrasitthiphol P, Wilkinson RN, Chouliaras KM, Liu K, Plant K, Sholapurkar R, Ratnayaka I, Herzog W, Bond G, Chico T, Bou-Gharios G, De Val S, Venous identity requires BMP signalling through ALK3. Nat Commun. 2019 Jan 28;10(1):453
1	J:149562 Roffers-Agarwal J, Gammill LS, Neuropilin receptors guide distinct phases of sensory and motor neuronal segmentation. Development. 2009 Jun;136(11):1879-88
1*	J:149474 Schwarz Q, Maden CH, Davidson K, Ruhrberg C, Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia. Development. 2009 Jun;136(11):1785-9
1	J:209482 Schwarz Q, Maden CH, Vieira JM, Ruhrberg C, Neuropilin 1 signaling guides neural crest cells to coordinate pathway choice with cell specification. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6164-9
1	J:221661 Wiszniak S, Mackenzie FE, Anderson P, Kabbara S, Ruhrberg C, Schwarz Q, Neural crest cell-derived VEGF promotes embryonic jaw extension. Proc Natl Acad Sci U S A. 2015 May 12;112(19):6086-91
1	J:152906 Xie J, Wu T, Xu K, Huang IK, Cleaver O, Huang CL, Endothelial-specific expression of WNK1 kinase is essential for angiogenesis and heart development in mice. Am J Pathol. 2009 Sep;175(3):1315-27